Fine synthesis, stereochemical and structural studies

4-(4-ethoxyphenyl)-5-(4-methoxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one, I. Burca, V. Badea, C. Deleanu, V.-N. Bercean, F. Péter, Molbank, 2023, 2023 (3), M1705. DOI: https://doi.org/10.3390/M1705

Synthesis and spectroscopic properties of novel indolizines and azaindolizines, A. Nicolescu, A. Airinei, E. Georgescu, F. Georgescu, R. Tigoianu, F. Dumitrascu, M. M. Popa, A. T. Marinoiu, C. Deleanu, Rev. Roum. Chim., 2023, 68 (5-6), 241-252. DOI: 10.33224/rrch.2023.68.5-6.07

Bezimidazolium bromide derivative inclusion complexes with native and modified beta-cyclodextrins, M. Balan-Porcarasu, A. Nicolescu, E. Georgescu, F. Georgescu, M. Cristea, C. Deleanu, B. C. Simionescu, Rev. Roum. Chim., 2023, 68 (3-4), 119-125. DOI: 10.33224/rrch.2023.68.3-4.01

Photophysical and biological properties of a strigolactone mimic derived from 1,8-naphthalic anhydride, I. Bala, A. Airinei, E. Georgescu, F. Oancea, F. Georgescu, A. Nicolescu, R. Tigoianu, C. Deleanu, Rev. Roum. Chim., 2022, 67 (1-2), 51-62. DOI: 10.33224/rrch.2022.67.1-2.03

Halogen bonded supramolecular assemblies constructed from azulene derivatives and perfluorinated di-/triiodobenzenes, A. Dogaru, A.A. Apostol, C. Maxim, M. Raduca, A.S. Novikov, A. Nicolescu, C. Deleanu, S. Nica, M. Andruh, CrystEngComm, 2023, 25 (37), 5243-5261. DOI: 10.1039/d3ce00752a

Synthesis and solvent dependent fluorescence of some piperidine-substituted naphthalimide derivatives and consequences for water sensing, R. Tigoianu, A. Airinei, E. Georgescu, A. Nicolescu, F. Georgescu, D.L. Isac, C. Deleanu, F. Oancea, Int. J. Molec. Sci., 2022, 23 (5), 2760. DOI: 10.3390/ijms23052760

1-Vinylazulenes with oxazolonic ring - potential ligands for metal ion detectors; synthesis and products properties, M. Cristea, L. Bîrzan, F. Dumitrascu, C Enache, V. Tecuceanu, A. Hanganu, C. Drăghici, C. Deleanu, A. Nicolescu, M. Maganu, A. C. Razus, Symmetry, 2021, 13 (7), 1209, p. 1-8. DOI: 10.3390/sym13071209

Benzimidazolium salts as starting materials or intermediates in 1,3-dipolar cycloadditions, A.-M. Macsim, E. Georgescu, F. Georgescu, P. Filip, A. Nicolescu, C. Deleanu, Monatsh. Chem., 2021, 152 (7), 845-852. DOI: 10.1007/s00706-021-02795-7

5-((8-Hydroxyquinolin-5-yl)diazenyl)-3-methyl-1H-pyrazole-4-carboxylic acid, I. Burca, V. Badea, C. Deleanu, V.-N. Bercean, Molbank, 2021, 2021 (2), M1238. DOI: 10.3390/M1238

Synthesis and structural analysis of complexes based on alpha-amino ketone derived from benzimidazole, M. D. Stanescu, C. Stefanov, F. Albota, A. Hirtopeanu, O. C. Oprea, N. Stanica, M. Ferbinteanu, J. Mol. Struct., 2021, 1228, 129716. DOI:10.1016/j.molstruc.2020.129716

Synthesis, photophysical properties and solvatochromic analysis of some naphthalene-1,8-dicarboxylic acid derivatives, A. Nicolescu, A. Airinei, E. Georgescu, F. Georgescu, R. Tigoianu, F. Oancea, C. Deleanu, J. Molec. Liquids, 2020, 303, 112626. DOI: 10.1016/j.molliq.2020.112626

A novel profluorescent paramagnetic diaza-crown ether: synthesis, characterization and alkaline metal-ion complexation, A. G. Coman, Cristina Stavarache, A. Păun, C. P. Codruța, N. D. Hădade, P. Ioniţă, M. Matache, RSC Adv., 2019, 9, 6078-6083. DOI: 10.1039/C8RA09828J.

Schiff bases containing a furoxan moiety as potential nitric oxide donors in plant tissues, E. Georgescu, A. Oancea, F. Georgescu, A. Nicolescu, E. I. Oprita, L. Vladulescu, M.-C. Vladulescu, F. Oancea, S. Shova, C. Deleanu, Plos One, 2018, 13 (7), e0198121. DOI 10.1371/journal.pone.0198121

New strigolactone mimics as exogenous signals for Rhizosphere organisms, F. Oancea, E. Georgescu, R. Matusova, F. Georgescu, A. Nicolescu, I. Raut, M.-L. Jecu, M.-C. Vladulescu, L. Vladulescu, C. Deleanu, Molecules, 2017, 22 (6), 961. DOI: 10.3390/molecules22060961

Isoxazole derivatives as new nitric oxide elicitors in plants, A. Oancea, E. Georgescu, F. Georgescu, A. Nicolescu, E. I. Oprita, C. Tudora, L. Vladulescu, M.-C. Vladulescu, F. Oancea, C. Deleanu, Beil. J. Org. Chem., 2017, 13, 659-664. DOI: 10.3762/bjoc.13.65

Fine tuning the outcome of 1,3-dipolar cycloaddition reactions of benzimidazolium ylides to activated alkynes, E. Georgescu, A. Nicolescu, F. Georgescu, F. Teodorescu, S. Shova, A.T. Marinoiu, F. Dumitrascu, C. Deleanu, Tetrahedron, 2016, 72 (19), 2507-2520. DOI: 10.1016/j.tet.2016.03.086

Novel one-pot, multicomponents synthetic strategy towards pyrrolo[1,2-a]benzimidazole and pyrrolo[1,2-a]quinoxaline derivatives, E. Georgescu, A. Nicolescu, F. Georgescu, S. Shova, F. Teodorescu, A.-M. Macsim, C. Deleanu, Synthesis, 2015, 47 (11), 1643-1655. DOI: 10.1055/s-0034-1380185

New highlights of the syntheses of pyrrolo[1,2-a]quinoxalin-4-ones, E. Georgescu, A. Nicolescu, F. Georgescu, F. Teodorescu, D. Marinescu, A.-M. Macsim, C. Deleanu, Beilstein J. Org. Chem., 2014, 10, 2377-2387. DOI: 10.3762/bjoc.10.248

Unexpected formation of N-(1-(2-aryl-hydrazono)isoindolin-2-yl)benzamides and their conversion into 1,2-(bis-1,3,4-oxadiazol-2-yl)benzenes, C. Paraschivescu, M. Matache, C. Dobrota, A. Nicolescu, C. Maxim, C. Deleanu, I. Farcasanu, N. Hădade, J. Org. Chem., 2013, 78 (6), 2670-2679. DOI: 10.1021/jo400023z

Unexpected formation of pyrrolo[1,2-a]quinoxaline derivatives during the multicomponent synthesis of pyrrolo[1,2-a]benzimidazoles, A. Nicolescu, C. Deleanu, E. Georgescu, F. Georgescu, A.-M. Iurascu, S. Shova, P. Filip, Tetrahedron Lett., 2013, 54, 1486-1488. DOI: 10.1016/j.tetlet.2013.01.036

Hydroacridines: ¹H and ¹³C NMR spectra of 9-substituted 1,2,3,4,5,6,7,8-octahydroacridines and their N-oxides, F. Potmischil, M. Marinescu, A. Nicolescu, C. Deleanu, Magn. Reson. Chem., 2009, 47 (12), 1031-1035. DOI: 10.1002/mrc.2507

Hydroacridines: ¹⁵N NMR chemical shifts of 9-substituted 1,2,3,4,5,6,7,8-octahydroacridines and their N-oxides. Taft, Swain-Lupton and other types of linear correlations, F. Potmischil, M. Marinescu, A. Nicolescu, C. Deleanu, M. Hillebrand, Magn. Reson. Chem., 2008, 46 (12), 1141-1147. DOI: 10.1002/mrc.2335

Saturated amine oxides. Hydroacridines: Effects of N-oxidation and of N-quaternization on the 15N NMR chemical shifts of N-methylpiperidine-derived mono-, bi- and tricycloaliphatic tertiary amines, F. Potmischil, H. Duddeck, A. Nicolescu, C. Deleanu, Magn. Reson. Chem., 2007, 45 (3), 231-235. DOI: 10.1002/mrc.1951

Solid state structure and solution behaviour of organoselenium(II) compounds containing 2-{X(CH2CH2)2NCH2}C6H4 groups (X = O, NMe), M. Kulcsar, A. Beleaga, C. Silvestru, A. Nicolescu, C. Deleanu, C. Todasca, A. Silvestru, J. Chem. Soc. Dalton Trans., 2007, 2187-2196. DOI: 10.1039/b702629c

Short-time sonolysis of chlorobenzene in the presence of Pd(II) salts and Pd(0), Carmen Stavarache, M. Vinatoru, R. Nishimura, Y. Maeda, Ultrason. Sonochem., 2004, 11 (6), 429-434. DOI: 10.1016/j.ultsonch.2003.09.001

The intramolecular asymmetric Pauson-Khand cyclization as a novel and general stereoselective route to benzindene prostacyclins: Synthesis of UT-15 (Treprostinil), R. M. Moriarty, N. Rani, L. A. Enache, M. S. Rao, H. Batra, L. Guo, R. A. Penmasta, J. P. Staszewski, S. M. Tuladhar, O. Prakash, D. Crich, A. Hirtopeanu, R. Gilardi, J. Org. Chem., 2004, 69 (6), 1890-1902. DOI: 10.1021/jo0347720

Sonolysis of chlorobenzene in Fenton-type aqueous systems, Carmen Stavarache, B. Yim, M. Vinatoru, Y. Maeda, Ultrason. Sonochem., 2002, 9 (6), 291-296. DOI: 10.1016/S1350-4177(02)00088-3

Hypervalent selenium compounds containing N-Se intramolecular interactions: synthesis, characterization and X-ray structures of [2-(Me2NCH2)C6H4]SeS9S)PR2 (R = Ph, OiPr), C. Deleanu, J. E. Drake, M. B. Hursthouse, M. Kulcsar, M. E. Light, A. Silvestru, Appl. Organomet. Chem., 2002, 16, 1-7. DOI: 10.1002/aoc.379

Hydroacridines: ¹H and ¹³C NMR spectra of sym-octahydroacridine, its 9-(3-pyridyl) and 9-(4-pyridyl) derivatives and the corresponding N(10)-oxides. An experimental approach to the diamagnetic anisotropy of the pyridine nucleus, F. Potmischil, C. Deleanu, M. Marinescu, M.D. Gheorghiu, Magn. Reson. Chem., 2002, 40 (3), 237-240. DOI: 10.1002/mrc.996

Contribution of chiral HPLC in tandem with polarimetric detection in the determination of absolute configuration by chemical interconversion method: Example in 1-(thi)oxothiazolinyl-3-(thi)oxothiazolinyl toluene atropisomer series, C. Roussel, N. Hart, B. Bonnet, C. Suteu, A. Hirtopeanu, V. Ch. Kravtsov, R. Luboradzki, N. Vanthuyne, Chirality, 2002, 14, (8), 665-673. DOI: 10.1002/chir.10125

Ni (II) complexes with [N3O] Schiff-base ligands bearing S-methylisothiosemicarbazide unit: design, synthesis and structure, J. Gradinaru, A. Forni, V. Druta, S. Quinci, A. Britchi, C. Deleanu, N. Gerbeleu, Inorg. Chim. Acta., 2002, 338, 169-181. DOI: 10.1016/S0020-1693(02)00910-6

Bis[oxo/thioxothiazolinyl] aromatic compounds - Stereochemical aspects, A. Hirtopeanu, M. Mihai, G. Mihai, C. Roussel, Heterocycles, 2000, 53, (8), 1669-1675. DOI: 10.3987/com-00-8904

Synthesis of isodrimenin from drim-8-en-7-one, P. F. Vlad, E. K. Gorincioi, M. N. Coltsa, C. Deleanu, Russ. Chem. Bull., 2000, 49 (3), 546 - 548. DOI: 10.1007/BF02494791

Bis[oxo/thioxothiazolinyl] aromatic compounds - Synthesis and conformational assignment, A. Hirtopeanu, C. Suteu, C. Uncuta, G. Mihai, C. Roussel, Eur. J. Org. Chem., 2000, 2000, (6), 1081-1090. DOI: 10.1002/(sici)1099-0690(200003)2000:6<1081::aid-ejoc1081>3.0.co;2-1

Pyrylium - mediated synthesis of n-(benzyloxy)pyridinium salts, T. S. Balaban, I. Tamasan, C. Deleanu, Liebigs Ann. Chem. 1992, 173-175. (since 1998 Eur. J. Org. Chem.).

Stereoisomerism due to restricted rotation in N-substituted-2,6-di-o-tolylpyridinium cations. A molecular design enabling unambiguous identification of isomers, C. Uncuta, I. Paun, A. Ghitescu, C. Deleanu, T.-S. Balaban, F. Chiraleu, M. D. Gheorghiu, A. T. Balaban, Tetrahedron Lett., 1990, 5645 - 5648. DOI: 10.1016/S0040-4039(00)97922-X

Vegetal, animal and human metabolomics

NMR proven albumin interaction with metabolites in complex mixtures, C. Duduianu, A. Nicolescu, M. Cristea, R. Stan, C. Deleanu, Rev. Roum. Chim., 2023, 68 (5-6), 253-259. DOI: 10.33224/rrch.2023.68.5-6.08

Diabetes-induced lipid panel particularities in hypertensive patients: A pilot NMR spectroscopy study, L.-A. Stanciulescu, A. Nicolescu, C. Duduianu, C. Deleanu, M. Dorobanțu, J. Hypertens. Res. 2022, 8 (4), 129-136.

Lipoprofiling assessed by NMR spectroscopy in patients with acute coronary syndromes: Is there a need for fasting prior to sampling?, L.-A. Stanciulescu, A. Scafa, C. Duduianu, R. Stan, A. Nicolescu, C. Deleanu, M. Dorobanțu, Diagnostics, 2022, 12 (7), 1675. DOI: 10.3390/diagnostics12071675

Lipoprotein profiles associated with exposure to poly- and perfluoroalkyl substances (PFASs) in the EuroMix human biomonitoring study, E. Papadopoulou, A. Nicolescu, L.S Haug, T. Husøy, C. Deleanu, H. Dirven, B. Lindeman, Environ. Pollut., 2022, 308, 119664. DOI: 10.1016/j.envpol.2022.119664

Saponification value of fats and oils as determined from ¹H-NMR data: the case of dairy fats, M. Ivanova, A. Hanganu, R. Dumitriu, M. Tociu, G. Ivanov, Cristina Stavarache, L. Popescu, A. Ghendov-Mosanu, R. Sturza, C. Deleanu, N.-A. Chira, Foods, 2022, 11, 1466. DOI: 10.3390/foods11101466

A real-life reproducibility assessment for NMR metabolomics, Cristina Stavarache, A. Nicolescu, C. Duduianu, G. L. Ailiesei, M. Balan-Porcăraşu, M. Cristea, A.-M. Macsim, O. Popa, Carmen Stavarache, A. Hîrtopeanu, L. Barbeş, R. Stan, H. Iovu, C. Deleanu, Diagnostics, 2022, 12 (3), 559. DOI: 10.3390/diagnostics12030559

Monitoring methylmalonic aciduria by NMR urinomics, A. Nicolescu, D. Blanita, C. Boiciuc, V. Hlistun, M. Cristea, D. Rotaru, L. Pinzari, A. Oglinda, A. Stamati, I. Tarcomnicu, A. Tutulan-Cunita, D. Stambouli, S. Gladun, N. Revenco, N. Usurelu, C. Deleanu, Molecules, 2020, 25 (22), 5312. DOI:10.3390/molecules25225312

A severe neonatal argininosuccinic aciduria case investigated by ¹H NMR spectroscopy, R. Vulturar, A. Chis, M. Baizat, A. Cozma, R. Suharoschi, A. Nicolescu, C. Deleanu, Rev. Chim., 2020, 71 (3), 210-218. DOI: 10.37358/RC.20.3.7990

Novel mutation in GALT gene in galactosemia patient with Group B Streptococcus Meningitis and acute liver failure, A. Grama, L. Blaga, A. Nicolescu, C. Deleanu, M. Militaru, S. S. Căinap, I. Pop, G. Tita, C. Sîrbe, O. Fufezan, M. A. Vintan, R. Vulturar, T. L. Pop, Medicina, 2019, 55 (4), 91. DOI: 10.3390/medicina55040091

Fatty acid composition of vegetable oils determined from ¹³C-NMR spectra, N. A. Chira, A. Nicolescu, R. Stan, S. Rosca, Rev. Chim., 2016, 67 (7), 1257-1263.

The ¹H NMR profile of healthy dog cerebrospinal fluid, M. Musteata, A. Nicolescu, G. Solcan, C. Deleanu, Plos One, 2013, 3 (12), e81192. DOI: 10.1371/journal.pone.0081192

The effect of therapeutic doses of paracetamol and aspirin on the NMR profile of urine at 400 MHz, A. Nicolescu, N. Simionescu, L. Ursu, C. Deleanu, B. C. Simionescu, Rev. Roum. Chim., 2012, 57 (7-8), 653-658.

Evaluation of the computational methods for determining vegetable oils composition using ¹H-NMR spectroscopy, N.-A. Chira, M.-C. Todasca, A. Nicolescu, A. Rosu, M. Nicolae, S.-I. Rosca, Rev. Chim., 2011, 62 (1), 42-46.

Diagnosis of type II diabetes based on non-glucose regions of ¹H NMR spectra of urine: a metabonomic approach, A. Nicolescu, B. Dolenko, T. Bezabeh, L.-I. Stefan, C. Ciurtin, E. Kovacs, I. C. P. Smith, B. C. Simionescu, C. Deleanu, Rev. Chim., 2011, 62 (12), 1150-1153.

Composition changes in wines produced by different growing techniques examined through ¹H-NMR spectroscopy, M.-C. Todasca, L. Fotescu, N.-A. Chira, C. Deleanu, S. Rosca, Rev. Chim., 2011, 62 (2), 131-134.

¹H-NMR urine metabolic profiling in type 1 diabetes Mellitus, L. I. Stefan, A. Nicolescu, S. Popa, M. Mota, E. Kovacs, C. Deleanu, Rev. Roum. Chim., 2010, 55 (11-12), 1033-1037.

Study of compositional changes in must during fermentation process using proton nuclear magnetic resonance spectroscopy, M.-C. Todaşcă, N. Chira, M. Avramescu, A. Rubeli, C. Deleanu, S. Rosca, Rev. Chim., 2008, 59 (10), 1101-1105.

Metabolic profiling of urine by ¹H-NMR spectroscopy. A critical assessment of interpreting metabolite concentrations for normal and diabetes groups, C. Ciurtin, A. Nicolescu, L.-I. Stefan, E. Kovacs, I. C. P. Smith, C. Deleanu, Rev. Chim., 2007, 52 (1), 51-55.

Identification and quantitative measurement by ¹H-NMR spectroscopy of several compounds present in Romanian wines, M.-C. Buzas, N. Chira, C. Deleanu, S. Rosca, Rev. Chim., 2003, 54 (10), 831-833.

Multicentre assessment of small molecule quantitation in human blood plasma using ¹H-NMR spectroscopy, J. C. Lindon and B. C. Sweatman, Listed participating Centres: C. Arus (Barcelona), S. Cerdan (Madrid), J. D. de Certaines (Rennes), C. Deleanu (Bucharest), R. D. Farrant and M. J. Seddon (Beckenham), J. R. Griffiths (London), D. Liebfritz and T. Derr (Bremen), L. le Moyec (Paris), J. K. Nicholson, M. L. Anthony and A. Tucker (London), F. Podo and A. Knijn (Rome), T. A. D. Smith (Surrey) and J. Vion-Dury (Marseille). J. Magn. Reson. Anal., 1996, 2, 66-74.

Esteri metilici ai acizilor grasi. Compusi etalon pentru atributia semnalelor in spectrele RMN de rezolutie inalta ale uleiurilor comestibile, C. Deleanu, C. Enache, M. T. Caproiu, G. Cornilescu, A. Hirtopeanu, Rev. Chim., 1994, 45 (12), 1046-1052.

Biomedical related materials and processes

Alternative solid activators from waste glass for one-part alkali-activated fly ash/red mud cements, N. Marin, C. Orbeci, L. Bobirică, I. Rău, C. Deleanu, E.I. Bîru, P.O. Stănescu, A.C. Berbecaru, E. Matei, C. Bobirică, Materials, 2023, 16 (20), 6707. DOI: 10.3390/ma16206707

Formulation of phytosomes with extracts of Ginger Rhizomes and Rosehips with improved bioavailability, antioxidant and anti-inflammatory effects in vivo, M. Deleanu, L. Toma, G. M. Sanda, T. Barbalata, L. S. Niculescu, A. V. Sima, C. Deleanu, L. Sacarescu, A. Suciu, G. Alexandru, I. Crișan, M. Popescu, C. S. Stancu, Pharmaceutics, 2023, 15 (4), 1066. DOI: 10.3390/pharmaceutics15041066

Crown ether-functionalized cellulose acetate membranes with potential applications in osseointegration, M. Oprea, A. M. Pandele, A. I. Nicoara, A. Nicolescu, C. Deleanu, S. I. Voicu, Int. J. Biol. Macromolec. 2023, 230, 123162. DOI: 10.1016/j.ijbiomac.2023.123162

Transport of magnetic polyelectrolyte capsules in various environments, Carmen Stavarache, M. Vinatoru, T. Mason, Coatings, 2022, 12 (2), 259. DOI: 10.3390/coatings12020259

3D Printable composite biomaterials based on GelMA and hydroxyapatite powders doped with cerium ions for bone tissue regeneration, R. L. Alexa, A. Cucuruz, C.-D. Ghitulica, G. Voicu, L.-R. Stamat (Balahura), S. Dinescu, G. M. Vlasceanu, Cristina Stavarache, R. Ianchis, H. Iovu, M. Costache, Int. J. Mol. Sci., 2022, 23 (3), 1841. DOI: 10.3390/ijms23031841

Electrospun nanofibrous membranes based on citric acid-functionalized chitosan containing rGO-TEPA with potential application in wound dressings, E. Cojocaru, J. Ghitman, G. Gradisteanu Pircalabioru, Cristina Stavarache, A. Serafim, E. Vasile, H. Iovu, Polymers, 2022, 14 (2), 294. DOI: 10.3390/polym14020294

Insightful characterization of sesamol-based polybenzoxazines: Effect of phenol and amine chain type on physical and nanomechanical properties, M. I Necolau, I. E. Bîru, J. Ghițman, Cristina Stavarache, H. Iovu, Polymer Testing, 2022, 110, 107578, DOI:10.1016/j.polymertesting.2022.107578

Enzymatic pre-treatment of grape seeds for an oil with higher antioxidant activity, M. Tociu, A. Hirtopeanu, M. D. Stanescu, Grasas Y Aceites, 2021, 72 (4), e434. DOI: 10.3989/gya.1000202

3D-Printed gelatin methacryloyl-based scaffolds with potential application in tissue engineering, R. L. Alexa, H. Iovu, J. Ghitman, A. Serafim, Cristina Stavarache, M.-M. Marin, R. Ianchis, Polymers, 2021, 13 (5), 727. DOI:10.3390/polym13050727

5-Aminosalicylic Acid loaded chitosan-carrageenan hydrogel beads with potential application for the treatment of inflammatory bowel disease, Cristina Stavarache, A. Ghebaur, S. Dinescu, I. Samoila, E. Vasile, G. M. Vlasceanu, H. Iovu, S. A. Gârea, Polymers, 2021, 13 (15), 2463. DOI: 10.3390/polym13152463

The effect of focused ultrasound on magnetic polyelectrolyte capsules loaded with dye when suspended in tissue-mimicking gel, Carmen Stavarache, M. Vinatoru, T. Mason, Curr. Drug Deliv., 2019, 16 (4), 355-363. DOI: 10.2174/1567201816666190103121313

Hyperpolarized water enhances two-dimensional proton NMR correlations: a new approach for molecular interactions, A. Sadet, Cristina Stavarache, M. Bacalum, M. Radu, G. Bodenhausen, D. Kurzbach, P. R. Vasos, J. Am. Chem. Soc., 2019, 141 (32), 12448-12452. DOI: 10.1021/jacs.9b03651.

Water hydrogen uptake in biomolecules detected via nuclear magnetic phosphorescence, A. Sadet, Cristina Stavarache, F. Teleanu, P. R. Vasos, Sci. Rep., 2019, 9, 17118. DOI:10.1038/s41598-019-53558-8.

Hyperpolarised NMR to follow water proton transport through membrane channels via exchange with biomolecules, V. V. Nastasa, Cristina Stavarache, A. Hanganu, A. Coroaba, A. Nicolescu, C. Deleanu, A. Sadet, P. Vasos, Faraday Discussions, 2018, 209, 67-82. DOI 10.1039/C8FD00021B

Long-lived states detect interactions between small molecules and diamagnetic metal ions, Cristina Stavarache, A. Hanganu, A. Paun, C. Paraschivescu M. Matache, P. R. Vasos, J. Magn. Reson., 2017, 284, 15-19. DOI: 10.1016/j.jmr.2017.09.001

Immobilized laccase on a new cryogel carrier and kinetics of two anthraquinone derivatives oxidation, M. D. Stanescu, A. Sanislav, R. V. Ivanov, A. Hirtopeanu, V. I. Lozinsky, Appl. Biochem. Biotechnol., 2011, 165 (7-8), 1789-1798. DOI: 10.1007/s12010-011-9395-8

Agro-food related studies

Aspects of ultrasonically assisted transesterification of various vegetable oils with methanol, Carmen Stavarache, M. Vinatoru, Y. Maeda, Ultrason. Sonochem., 2007, 14 (3), 380-386. DOI: 10.1016/j.ultsonch.2006.08.004

Ultrasonically driven continuous process for vegetable oil transesterification, Carmen Stavarache, M. Vinatoru, Y. Maeda, H. Bandow, Ultrason. Sonochem., 2007, 14 (3),  413-417. DOI: 10.1016/j.ultsonch.2006.09.014

Ultrasonic versus silent methylation of vegetable oils, Carmen Stavarache, M. Vinatoru, Y. Maeda, Ultrason. Sonochem., 2006, 13 (5), 401-407. DOI: 10.1016/j.ultsonch.2005.08.001

Nuclear Magnetic Resonance Spectroscopy Applications. Food, C. Deleanu, in “Encyclopedia of Analytical Science”, 2nd Edn, (P. J. Worsfold, A. Townshend, and C. F. Poole, Eds.), Elsevier, Oxford, 2005. ISBN: 0-12-764100-9, Volume 6, pp. 303-315.

Fatty acids methyl esters from vegetable oil by means of ultrasonic energy, Carmen Stavarache, M. Vinatoru, R. Nishimura, Y. Maeda, Ultrason. Sonochem., 2005, 12 (5), 367-372. DOI: 10.1016/j.ultsonch.2004.04.001

Conversion of vegetable oil to biodiesel using ultrasonic irradiation, Carmen Stavarache, M. Vinatoru, R. Nishimura, Y. Maeda, Chem. Lett., 2003, 32 (8), 716-717. DOI: 10.1246/cl.2003.716

Applications of high field high resolution nuclear magnetic resonance spectroscopy to the authentication of edible oils, C. Deleanu, M. T. Caproiu, G. Cornilescu, C. Enache, A. Hirtopeanu, in: “Food Authentication by Spectroscopic Techniques (FAST). A QUEST Action Group Guideline Document”, (Eds. M. Lees and C. N. G. Scotter), Commission of the European Communities, Brussels, 1994, ISBN: 0 9523455 6 0, Printed by E. P. Lowe Limited, Broadway, UK, pp. 29 - 38.

Mimicking living matter mechanisms by five-dimensional chemistry (5D-NanoP) - PN-III-P4-ID-PCCF-2016-0050 (Contract No. 4/2018) - https://www.intelcentru.ro/5D-nanoP/

Project abstract: Mimicking the living matter mechanism of cooperation by complementarity represents one of the most challenging tasks of supramolecular chemistry. The momentary solution consists in using particularly designed molecular unimers, endowed with the necessary amount of chemical information. The 5D-nanoP project is dedicated to interfacing the fundamental research area of constitutional dynamic chemistry with the practical approaches of medicinal chemistry and biomedical applications. In the spirit of a metaphor of Jean-Marie Lehn (Nobel Prize in Chemistry, 1987), the project aims to materialize the concept of 5D chemistry in designing, synthesizing, characterizing, and using molecules with conditional affinity, to build versatile supramolecular nanoplatforms able to vectorize compounds of pharmaceutical or biochemical relevance, all of them involved in physiologic and pathologic processes at cell- and tissue-level. The project is adding the layer of 5D chemistry over the backgrounds of molecular assembling line techniques, to produce particulate nanoplatforms, self-assemblable in the virtue of the chemical information stored by the designed unimer molecules. Two modern techniques of building dynamic chemical structures will be considered: (i) the use of self-immolative linkers, and (ii) the space stepwise and time phased assisted synthesis. In order to prove the applicability of the produced nanoplatforms, an ex vivo cell cultivation system will be developed, to emulate tissue/tumor niches. Seven teams are involved in the 5D-nanoP project, covering the main addressed research areas: (i) the in silico molecular design, (ii) the development of a unimers chemical library, (iii) the development of a molecular assembling line, (iv) the conjugation of the developed platforms with chemical species of biomedical interest, (v) the build of ex vivo emulating niches, and (vi) the bio-oriented assessment of the nanoconstructs efficacy.

Our group has long term collaborations with groups from the following institutions:

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